il-2 receptor beta chain in t cell activation
| PAG Title | il-2 receptor beta chain in t cell activation |
| PAG ID | WAG001458 |
| Type | P |
| Source Link |  BioCarta |
| Publication Reference | NA |
| PAG Description | The IL-2 receptor is a key component of immune sigling and is required for the activation, proliferation, and survival of T cells. This receptor is composed of three polypeptide chains, the alpha, beta and gamma chains. The IL-2 receptor gamma chain is a common component for several other cytokine receptors, including IL-4, IL-7, IL-9 and IL-15. The IL-2 receptor beta chain is essential for IL-2 sigling and is also a component of the IL-15 receptor complex. The polypeptides of the IL-2 receptor do not themselves have intrinsic catalytic activity, but interact with cytoplasmic sigling proteins to transduce sigls. |
| Species | Homo sapiens |
| nCoCo Score | 5,511 |
| Base PAG ID | WAG001458 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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